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Versatility and Invariance in the Evolution of Homologous Heteromeric Interfaces

Evolutionary pressures act on protein complex interfaces so that they preserve their complementarity. Nonetheless, the elementary interactions which compose the interface are highly versatile throughout evolution. Understanding and characterizing interface plasticity across evolution is a fundamenta...

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Detalles Bibliográficos
Autores principales: Andreani, Jessica, Faure, Guilhem, Guerois, Raphaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431345/
https://www.ncbi.nlm.nih.gov/pubmed/22952442
http://dx.doi.org/10.1371/journal.pcbi.1002677