Inhibition of Candida parapsilosis Fatty Acid Synthase (Fas2) Induces Mitochondrial Cell Death in Serum

We have recently observed that a fatty acid auxotrophic mutant (fatty acid synthase, Fas2Δ/Δ) of the emerging human pathogenic yeast Candida parapsilosis dies after incubation in various media including serum. In the present study we describe the mechanism for cell death induced by serum and glucose...

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Detalles Bibliográficos
Autores principales: Nguyen, Long Nam, Cesar, Gabriele Vargas, Le, Giang Thi Thu, Silver, David L., Nimrichter, Leonardo, Nosanchuk, Joshua D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431346/
https://www.ncbi.nlm.nih.gov/pubmed/22952445
http://dx.doi.org/10.1371/journal.ppat.1002879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431346/
https://www.ncbi.nlm.nih.gov/pubmed/22952445
http://dx.doi.org/10.1371/journal.ppat.1002879

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