Reprogramming to Pluripotency Can Conceal Somatic Cell Chromosomal Instability

The discovery that somatic cells are reprogrammable to pluripotency by ectopic expression of a small subset of transcription factors has created great potential for the development of broadly applicable stem-cell-based therapies. One of the concerns regarding the safe use of induced pluripotent stem...

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Detalles Bibliográficos
Autores principales: Hamada, Masakazu, Malureanu, Liviu A., Wijshake, Tobias, Zhou, Wei, van Deursen, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431347/
https://www.ncbi.nlm.nih.gov/pubmed/22952451
http://dx.doi.org/10.1371/journal.pgen.1002913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431347/
https://www.ncbi.nlm.nih.gov/pubmed/22952451
http://dx.doi.org/10.1371/journal.pgen.1002913

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