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Reprogramming to Pluripotency Can Conceal Somatic Cell Chromosomal Instability

The discovery that somatic cells are reprogrammable to pluripotency by ectopic expression of a small subset of transcription factors has created great potential for the development of broadly applicable stem-cell-based therapies. One of the concerns regarding the safe use of induced pluripotent stem...

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Detalles Bibliográficos
Autores principales:	Hamada, Masakazu, Malureanu, Liviu A., Wijshake, Tobias, Zhou, Wei, van Deursen, Jan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431347/ https://www.ncbi.nlm.nih.gov/pubmed/22952451 http://dx.doi.org/10.1371/journal.pgen.1002913

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