Telomere Length Affects the Frequency and Mechanism of Antigenic Variation in Trypanosoma brucei

Trypanosoma brucei is a master of antigenic variation and immune response evasion. Utilizing a genomic repertoire of more than 1000 Variant Surface Glycoprotein-encoding genes (VSGs), T. brucei can change its protein coat by “switching” from the expression of one VSG to another. Each active VSG is m...

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Detalles Bibliográficos
Autores principales: Hovel-Miner, Galadriel A., Boothroyd, Catharine E., Mugnier, Monica, Dreesen, Oliver, Cross, George A. M., Papavasiliou, F. Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431348/
https://www.ncbi.nlm.nih.gov/pubmed/22952449
http://dx.doi.org/10.1371/journal.ppat.1002900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431348/
https://www.ncbi.nlm.nih.gov/pubmed/22952449
http://dx.doi.org/10.1371/journal.ppat.1002900

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