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Telomere Length Affects the Frequency and Mechanism of Antigenic Variation in Trypanosoma brucei
Trypanosoma brucei is a master of antigenic variation and immune response evasion. Utilizing a genomic repertoire of more than 1000 Variant Surface Glycoprotein-encoding genes (VSGs), T. brucei can change its protein coat by “switching” from the expression of one VSG to another. Each active VSG is m...
Autores principales: | Hovel-Miner, Galadriel A., Boothroyd, Catharine E., Mugnier, Monica, Dreesen, Oliver, Cross, George A. M., Papavasiliou, F. Nina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431348/ https://www.ncbi.nlm.nih.gov/pubmed/22952449 http://dx.doi.org/10.1371/journal.ppat.1002900 |
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