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Beta Cell Count Instead of Beta Cell Mass to Assess and Localize Growth in Beta Cell Population following Pancreatic Duct Ligation in Mice

BACKGROUND: Pancreatic-tail duct ligation (PDL) in adult rodents has been reported to induce beta cell generation and increase beta cell mass but increases in beta cell number have not been demonstrated. This study examines whether PDL increases beta cell number and whether this is caused by neogene...

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Detalles Bibliográficos
Autores principales: Chintinne, Marie, Stangé, Geert, Denys, Bart, Ling, Zhidong, In ‘t Veld, Peter, Pipeleers, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431350/
https://www.ncbi.nlm.nih.gov/pubmed/22952825
http://dx.doi.org/10.1371/journal.pone.0043959