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Transport Properties of Melanosomes along Microtubules Interpreted by a Tug-of-War Model with Loose Mechanical Coupling

In this work, we explored theoretically the transport of organelles driven along microtubules by molecular motors of opposed polarities using a stochastic model that considers a Langevin dynamics for the cargo, independent cargo-motor linkers and stepping motion for the motors. It has been recently...

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Detalles Bibliográficos
Autores principales: Bouzat, Sebastián, Levi, Valeria, Bruno, Luciana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431353/
https://www.ncbi.nlm.nih.gov/pubmed/22952716
http://dx.doi.org/10.1371/journal.pone.0043599