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Photo-Oxidation Products of Skin Surface Squalene Mediate Metabolic and Inflammatory Responses to Solar UV in Human Keratinocytes

The study aimed to identify endogenous lipid mediators of metabolic and inflammatory responses of human keratinocytes to solar UV irradiation. Physiologically relevant doses of solar simulated UVA+UVB were applied to human skin surface lipids (SSL) or to primary cultures of normal human epidermal ke...

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Detalles Bibliográficos
Autores principales: Kostyuk, Vladimir, Potapovich, Alla, Stancato, Andrea, De Luca, Chiara, Lulli, Daniela, Pastore, Saveria, Korkina, Liudmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431355/
https://www.ncbi.nlm.nih.gov/pubmed/22952984
http://dx.doi.org/10.1371/journal.pone.0044472