Cargando…

The Minimal Deneddylase Core of the COP9 Signalosome Excludes the Csn6 MPN(−) Domain

The COP9 signalosome (CSN) is a eukaryotic protein complex, which regulates a wide range of biological processes mainly through modulating the cullin ubiquitin E3 ligases in the ubiquitin-proteasome pathway. The CSN possesses a highly conserved deneddylase activity that centers at the JAMM motif of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pick, Elah, Golan, Amnon, Zimbler, Jacob Z., Guo, Liquan, Sharaby, Yehonatan, Tsuge, Tomohiko, Hofmann, Kay, Wei, Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431379/ https://www.ncbi.nlm.nih.gov/pubmed/22956996 http://dx.doi.org/10.1371/journal.pone.0043980

Ejemplares similares

Role of the COP9 Signalosome (CSN) in Cardiovascular Diseases
por: Milic, Jelena, et al.
Publicado: (2019)

Control of Multicellular Development by the Physically Interacting Deneddylases DEN1/DenA and COP9 Signalosome
por: Christmann, Martin, et al.
Publicado: (2013)

COP9-Signalosome deneddylase activity is enhanced by simultaneous neddylation: insights into the regulation of an enzymatic protein complex
por: Bornstein, Gil, et al.
Publicado: (2015)

Fungal COP9 signalosome assembly requires connection of two trimeric intermediates for integration of intrinsic deneddylase
por: Bakti, Fruzsina, et al.
Publicado: (2023)

Structural and Biochemical Characterization of the Cop9 Signalosome CSN5/CSN6 Heterodimer
por: Birol, Melissa, et al.
Publicado: (2014)

Saccharomyces cerevisiae as a Toolkit for COP9 Signalosome Research
por: Harshuk-Shabso, Dana, et al.
Publicado: (2021)

The COP9 signalosome subunit 6 (CSN6): a potential oncogene
por: Zhang, Shang-Nuan, et al.
Publicado: (2013)

Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy
por: Pearce, Claire, et al.
Publicado: (2009)

Prognostic and therapeutic significance of COP9 signalosome subunit CSN5 in prostate cancer
por: Mazzu, Ying Z., et al.
Publicado: (2022)

Dual function of Rpn5 in two PCI complexes, the 26S proteasome and COP9 signalosome
por: Yu, Zanlin, et al.
Publicado: (2011)

Overexpression of COP9 signalosome subunits, CSN7A and CSN7B, exerts different effects on adipogenic differentiation
por: Huang, Xiaohua, et al.
Publicado: (2016)

Downregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stability
por: Peth, Andreas, et al.
Publicado: (2007)

The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation
por: Pacurar, Daniel Ioan, et al.
Publicado: (2017)

CSN5A Subunit of COP9 Signalosome Temporally Buffers Response to Heat in Arabidopsis
por: Singh, Amit Kumar, et al.
Publicado: (2019)

COP9 Signalosome CSN4 and CSN5 Subunits Are Involved in Jasmonate-Dependent Defense Against Root-Knot Nematode in Tomato
por: Shang, Yifen, et al.
Publicado: (2019)

Erratum: The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation
por: Pacurar, Daniel Ioan, et al.
Publicado: (2017)

The eta7/csn3-3 Auxin Response Mutant of Arabidopsis Defines a Novel Function for the CSN3 Subunit of the COP9 Signalosome
por: Huang, He, et al.
Publicado: (2013)

CSN6, a subunit of the COP9 signalosome, is involved in early response to iron deficiency in Oryza sativa
por: Tan, Song, et al.
Publicado: (2016)

The CSN/COP9 Signalosome Regulates Synaptonemal Complex Assembly during Meiotic Prophase I of Caenorhabditis elegans
por: Brockway, Heather, et al.
Publicado: (2014)

Identification of COP9 Signalosome Subunit Genes in Bactrocera dorsalis and Functional Analysis of csn3 in Female Fecundity
por: Zhang, Jing, et al.
Publicado: (2019)

The Proteasome Lid Triggers COP9 Signalosome Activity during the Transition of Saccharomyces cerevisiae Cells into Quiescence
por: Bramasole, Laylan, et al.
Publicado: (2019)

Inhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline
por: Pulvino, Mary, et al.
Publicado: (2015)

The CSN3 subunit of the COP9 signalosome interacts with the HD region of Sos1 regulating stability of this GEF protein
por: Zarich, Natasha, et al.
Publicado: (2019)

Essential Role of COP9 Signalosome Subunit 5 (Csn5) in Insect Pathogenicity and Asexual Development of Beauveria bassiana
por: Mou, Ya-Ni, et al.
Publicado: (2021)

COP9 signalosome subunit 6 (CSN6) regulates E6AP/UBE3A in cervical cancer
por: Gao, Shujun, et al.
Publicado: (2015)

A Subunit of the COP9 Signalosome, MoCsn6, Is Involved in Fungal Development, Pathogenicity, and Autophagy in Rice Blast Fungus
por: Shen, Zi-Fang, et al.
Publicado: (2022)

COP9 Signalosome Component JAB1/CSN5 Is Necessary for T Cell Signaling through LFA-1 and HIV-1 Replication
por: Kinoshita, Shigemi M., et al.
Publicado: (2012)

CSN5A Subunit of COP9 Signalosome Is Required for Resetting Transcriptional Stress Memory after Recurrent Heat Stress in Arabidopsis
por: Singh, Amit Kumar, et al.
Publicado: (2021)

Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome
por: Menon, Suchithra, et al.
Publicado: (2008)

Proteomic analysis reveals that COP9 signalosome complex subunit 7A (CSN7A) is essential for the phase transition of migratory locust
por: Tong, Xi-Wen, et al.
Publicado: (2015)

CSN6-COP1 axis in cancer
por: Choi, Hyun Ho, et al.
Publicado: (2015)

Prediction of a common structural scaffold for proteasome lid, COP9-signalosome and eIF3 complexes
por: Scheel, Hartmut, et al.
Publicado: (2005)

Conservation of the COP9/signalosome in budding yeast
por: Wee, Susan, et al.
Publicado: (2002)

Targeting the COP9 signalosome for cancer therapy
por: Du, Wenqi, et al.
Publicado: (2022)

Meloidogyne incognita PASSE-MURAILLE (MiPM) Gene Encodes a Cell-Penetrating Protein That Interacts With the CSN5 Subunit of the COP9 Signalosome
por: Bournaud, Caroline, et al.
Publicado: (2018)

SlBBX20 interacts with the COP9 signalosome subunit SlCSN5-2 to regulate anthocyanin biosynthesis by activating SlDFR expression in tomato
por: Luo, Dan, et al.
Publicado: (2021)

Crosstalk between the NF-κB activating IKK-complex and the CSN signalosome
por: Orel, Lukas, et al.
Publicado: (2010)

The Evolution of COP9 Signalosome in Unicellular and Multicellular Organisms
por: Barth, Emanuel, et al.
Publicado: (2016)

Tackling the crystallographic structure determination of the COP9 signalosome
por: Bunker, Richard D.
Publicado: (2016)

Targeted inhibition of the COP9 signalosome for treatment of cancer
por: Schlierf, Anita, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_iq64n6ft66g6d63tm56e12hovn