Expression of Human Paraoxonase 1 Decreases Superoxide Levels and Alters Bacterial Colonization in the Gut of Drosophila melanogaster

Paraoxonases (PON) are a family of proteins (PON1, 2 and 3) with multiple enzymatic activities. PON1 interferes with homoserine lactone-mediated quorum sensing in bacteria and with reactive oxygen species (ROS) in humans and mice. PON1 gene mutations have been linked to multiple traits, including ag...

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Detalles Bibliográficos
Autores principales: Pezzulo, Alejandro A., Hornick, Emma E., Rector, Michael V., Estin, Miriam, Reisetter, Anna C., Taft, Peter J., Butcher, Stephen C., Carter, A. Brent, Manak, J. Robert, Stoltz, David A., Zabner, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431398/
https://www.ncbi.nlm.nih.gov/pubmed/22952763
http://dx.doi.org/10.1371/journal.pone.0043777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431398/
https://www.ncbi.nlm.nih.gov/pubmed/22952763
http://dx.doi.org/10.1371/journal.pone.0043777

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