Vigabatrin-Induced Retinal Toxicity Is Partially Mediated by Signaling in Rod and Cone Photoreceptors

Vigabatrin (VGB) is a commonly prescribed antiepileptic drug designed to inhibit GABA-transaminase, effectively halting seizures. Unfortunately, VGB treatment is also associated with the highest frequencies of peripheral visual field constriction of any of the antiepileptic drugs and the mechanisms...

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Detalles Bibliográficos
Autores principales: Yang, Jin, Naumann, Matthew C., Tsai, Yi-Ting, Tosi, Joaquin, Erol, Deniz, Lin, Chyuan-Sheng, Davis, Richard J., Tsang, Stephen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431405/
https://www.ncbi.nlm.nih.gov/pubmed/22970106
http://dx.doi.org/10.1371/journal.pone.0043889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431405/
https://www.ncbi.nlm.nih.gov/pubmed/22970106
http://dx.doi.org/10.1371/journal.pone.0043889

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