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Co-activation of multiple tightly-coupled calcium channels triggers spontaneous release of GABA

Voltage-activated Ca(2+) channels (VACCs) mediate Ca(2+) influx to trigger action potential-evoked neurotransmitter release but the mechanism by which Ca(2+) regulates spontaneous transmission is unclear. Here we show VACCs are the major physiological triggers for spontaneous release at murine neoco...

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Detalles Bibliográficos
Autores principales: Williams, Courtney, Chen, Wenyan, Lee, Chia-Hsueh, Yaeger, Daniel, Vyleta, Nicholas P., Smith, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431448/
https://www.ncbi.nlm.nih.gov/pubmed/22842148
http://dx.doi.org/10.1038/nn.3162