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Co-activation of multiple tightly-coupled calcium channels triggers spontaneous release of GABA
Voltage-activated Ca(2+) channels (VACCs) mediate Ca(2+) influx to trigger action potential-evoked neurotransmitter release but the mechanism by which Ca(2+) regulates spontaneous transmission is unclear. Here we show VACCs are the major physiological triggers for spontaneous release at murine neoco...
Autores principales: | Williams, Courtney, Chen, Wenyan, Lee, Chia-Hsueh, Yaeger, Daniel, Vyleta, Nicholas P., Smith, Stephen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431448/ https://www.ncbi.nlm.nih.gov/pubmed/22842148 http://dx.doi.org/10.1038/nn.3162 |
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