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Predicting cell-type–specific gene expression from regions of open chromatin
Complex patterns of cell-type–specific gene expression are thought to be achieved by combinatorial binding of transcription factors (TFs) to sequence elements in regulatory regions. Predicting cell-type–specific expression in mammals has been hindered by the oftentimes unknown location of distal reg...
Autores principales: | Natarajan, Anirudh, Yardımcı, Galip Gürkan, Sheffield, Nathan C., Crawford, Gregory E., Ohler, Uwe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431488/ https://www.ncbi.nlm.nih.gov/pubmed/22955983 http://dx.doi.org/10.1101/gr.135129.111 |
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