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Voltage-sensing phosphatase reveals temporal regulation of TRPC3/C6/C7 channels by membrane phosphoinositides

TRPC3/C6/C7 channels, a subgroup of classical/canonical TRP channels, are activated by diacylglycerol produced via activation of phospholipase C (PLC)-coupled receptors. Recognition of the physiological importance of these channels has been steadily growing, but the mechanism by which they are regul...

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Detalles Bibliográficos
Autores principales: Itsuki, Kyohei, Imai, Yuko, Okamura, Yasushi, Abe, Kihachiro, Inoue, Ryuji, Mori, Masayuki X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431592/
https://www.ncbi.nlm.nih.gov/pubmed/22760061
http://dx.doi.org/10.4161/chan.20883