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Opticin Exerts Its Anti-angiogenic Activity by Regulating Extracellular Matrix Adhesiveness

Opticin is an extracellular matrix glycoprotein that we identified associated with the collagen network of the vitreous humor of the eye. Recently, we discovered that opticin possesses anti-angiogenic activity using a murine oxygen-induced retinopathy model: here, we investigate the underlying mecha...

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Detalles Bibliográficos
Autores principales: Le Goff, Magali M., Sutton, Matthew J., Slevin, Mark, Latif, Ayse, Humphries, Martin J., Bishop, Paul N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431625/
https://www.ncbi.nlm.nih.gov/pubmed/22669977
http://dx.doi.org/10.1074/jbc.M111.331157