Implication of Tumor Microenvironment in Chemoresistance: Tumor-Associated Stromal Cells Protect Tumor Cells from Cell Death

Tumor development principally occurs following the accumulation of genetic and epigenetic alterations in tumor cells. These changes pave the way for the transformation of chemosensitive cells to chemoresistant ones by influencing the uptake, metabolism, or export of drugs at the cellular level. Nume...

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Detalles Bibliográficos
Autores principales: Castells, Magali, Thibault, Benoît, Delord, Jean-Pierre, Couderc, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431813/
https://www.ncbi.nlm.nih.gov/pubmed/22949815
http://dx.doi.org/10.3390/ijms13089545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431813/
https://www.ncbi.nlm.nih.gov/pubmed/22949815
http://dx.doi.org/10.3390/ijms13089545

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