Cargando…

The Metalloporphyrin Antioxidant, MnTE-2-PyP, Inhibits Th2 Cell Immune Responses in an Asthma Model

MnTE-2-PyP, a superoxide dismutase mimetic, inhibited OVA-induced airway inflammation in mice suggesting an effect on Th2 responsiveness. Thus, we hypothesized that MnTE-2-PyP may alter dendritic cell-Th2 interactions. Bone marrow derived dendritic cells (DC) and OVA(323–339)-specific Th2 cells were...

Descripción completa

Detalles Bibliográficos
Autores principales: Jungsuwadee, Paiboon, Weaver, Michael R., Gally, Fabienne, Oberley-Deegan, Rebecca E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431828/
https://www.ncbi.nlm.nih.gov/pubmed/22949830
http://dx.doi.org/10.3390/ijms13089785