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The Metalloporphyrin Antioxidant, MnTE-2-PyP, Inhibits Th2 Cell Immune Responses in an Asthma Model
MnTE-2-PyP, a superoxide dismutase mimetic, inhibited OVA-induced airway inflammation in mice suggesting an effect on Th2 responsiveness. Thus, we hypothesized that MnTE-2-PyP may alter dendritic cell-Th2 interactions. Bone marrow derived dendritic cells (DC) and OVA(323–339)-specific Th2 cells were...
Autores principales: | Jungsuwadee, Paiboon, Weaver, Michael R., Gally, Fabienne, Oberley-Deegan, Rebecca E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431828/ https://www.ncbi.nlm.nih.gov/pubmed/22949830 http://dx.doi.org/10.3390/ijms13089785 |
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