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Synthesis of Triptorelin Lactate Catalyzed by Lipase in Organic Media

Triptorelin lactate was successfully synthesized by porcine pancreatic lipase (PPL) in organic solvents. The effects of acyl donor, substrate ratio, organic solvent, temperature, and water activity were investigated. Under the optimum conditions, a yield of 30% for its ester could be achieved in the...

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Detalles Bibliográficos
Autores principales: Zhuang, Hong, Wang, Zhi, Wang, Jiaxin, Zhang, Hong, Xun, Erna, Chen, Ge, Yue, Hong, Tang, Ning, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431840/
https://www.ncbi.nlm.nih.gov/pubmed/22949842
http://dx.doi.org/10.3390/ijms13089971