Effects of a Buried Cysteine-To-Serine Mutation on Yeast Triosephosphate Isomerase Structure and Stability

All the members of the triosephosphate isomerase (TIM) family possess a cystein residue (Cys126) located near the catalytically essential Glu165. The evolutionarily conserved Cys126, however, does not seem to play a significant role in the catalytic activity. On the other hand, substitution of this...

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Detalles Bibliográficos
Autores principales: Hernández-Santoyo, Alejandra, Domínguez-Ramírez, Lenin, Reyes-López, César A., González-Mondragón, Edith, Hernández-Arana, Andrés, Rodríguez-Romero, Adela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431843/
https://www.ncbi.nlm.nih.gov/pubmed/22949845
http://dx.doi.org/10.3390/ijms130810010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431843/
https://www.ncbi.nlm.nih.gov/pubmed/22949845
http://dx.doi.org/10.3390/ijms130810010

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