2,3-Dihydro-1H-cyclopenta[b]quinoline Derivatives as Acetylcholinesterase Inhibitors—Synthesis, Radiolabeling and Biodistribution

In the present study we describe the synthesis and biological assessment of new tacrine analogs in the course of inhibition of acetylcholinesterase. The obtained molecules were synthesized in a condensation reaction between activated 6-BOC-hydrazinopyridine-3-carboxylic acid and 8-aminoalkyl derivat...

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Detalles Bibliográficos
Autores principales: Szymański, Paweł, Lázničková, Alice, Lázniček, Milan, Bajda, Marek, Malawska, Barbara, Markowicz, Magdalena, Mikiciuk-Olasik, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431846/
https://www.ncbi.nlm.nih.gov/pubmed/22949848
http://dx.doi.org/10.3390/ijms130810067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431846/
https://www.ncbi.nlm.nih.gov/pubmed/22949848
http://dx.doi.org/10.3390/ijms130810067

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