Characterization of Aptamer-Protein Complexes by X-ray Crystallography and Alternative Approaches

Aptamers are oligonucleotide ligands, either RNA or ssDNA, selected for high-affinity binding to molecular targets, such as small organic molecules, proteins or whole microorganisms. While reports of new aptamers are numerous, characterization of their specific interaction is often restricted to the...

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Detalles Bibliográficos
Autores principales: Ruigrok, Vincent J. B., Levisson, Mark, Hekelaar, Johan, Smidt, Hauke, Dijkstra, Bauke W., van der Oost, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431876/
https://www.ncbi.nlm.nih.gov/pubmed/22949878
http://dx.doi.org/10.3390/ijms130810537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431876/
https://www.ncbi.nlm.nih.gov/pubmed/22949878
http://dx.doi.org/10.3390/ijms130810537

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