Antisense Oligonucleotide Against Clusterin Regulates Human Hepatocellular Carcinoma Invasion Through Transcriptional Regulation of Matrix Metalloproteinase-2 and E-Cadherin

Secreted clusterin (sCLU) has been shown to be overexpressed in metastatic hepatocellular carcinoma (HCC) tissue, and its overexpression in HCC cells increases cell migration and the formation of liver metastatic tumor nodules in vivo. In this study, we tested the hypothesis that sCLU plays a role i...

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Detalles Bibliográficos
Autores principales: Chen, Dong, Wang, Yan, Zhang, Kejun, Jiao, Xuelong, Yan, Bomin, Liang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431880/
https://www.ncbi.nlm.nih.gov/pubmed/22949882
http://dx.doi.org/10.3390/ijms130810594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431880/
https://www.ncbi.nlm.nih.gov/pubmed/22949882
http://dx.doi.org/10.3390/ijms130810594

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