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Preparation and in vitro studies of MRI-specific superparamagnetic iron oxide antiGPC3 probe for hepatocellular carcinoma

BACKGROUND: The aim of this study was to develop an antiGPC3-ultrasuperparamagnetic iron oxide (USPIO) probe for early detection of hepatocellular carcinoma. METHODS: GPC3 and AFP receptors were selected as biomarkers and conjugated with USPIO nanoparticles coated by dextran with carboxylate groups...

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Detalles Bibliográficos
Autores principales: Li, Youwei, Chen, Zhengguang, Li, Fei, Wang, Jichen, Zhang, Zongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431973/
https://www.ncbi.nlm.nih.gov/pubmed/22956868
http://dx.doi.org/10.2147/IJN.S32196