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A tissue biopsy-based epigenetic multiplex PCR assay for prostate cancer detection

BACKGROUND: PSA-directed prostate cancer screening leads to a high rate of false positive identifications and an unnecessary biopsy burden. Epigenetic biomarkers have proven useful, exhibiting frequent and abundant inactivation of tumor suppressor genes through such mechanisms. An epigenetic, multip...

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Detalles Bibliográficos
Autores principales: Van Neste, Leander, Bigley, Joseph, Toll, Adam, Otto, Gaëtan, Clark, James, Delrée, Paul, Van Criekinge, Wim, Epstein, Jonathan I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431995/
https://www.ncbi.nlm.nih.gov/pubmed/22672250
http://dx.doi.org/10.1186/1471-2490-12-16