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A tissue biopsy-based epigenetic multiplex PCR assay for prostate cancer detection
BACKGROUND: PSA-directed prostate cancer screening leads to a high rate of false positive identifications and an unnecessary biopsy burden. Epigenetic biomarkers have proven useful, exhibiting frequent and abundant inactivation of tumor suppressor genes through such mechanisms. An epigenetic, multip...
Autores principales: | Van Neste, Leander, Bigley, Joseph, Toll, Adam, Otto, Gaëtan, Clark, James, Delrée, Paul, Van Criekinge, Wim, Epstein, Jonathan I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431995/ https://www.ncbi.nlm.nih.gov/pubmed/22672250 http://dx.doi.org/10.1186/1471-2490-12-16 |
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