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Leukotriene D(4) and Interleukin-13 Cooperate to Increase the Release of Eotaxin-3 by Airway Epithelial Cells

INTRODUCTION: Airway epithelial cells play a central role in the physiopathology of asthma. They release eotaxins when treated with T(H)2 cytokines such as interleukin (IL)-4 or IL-13, and these chemokines attract eosinophils and potentiate the biosynthesis of cysteinyl leukotrienes (cysLTs), which...

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Detalles Bibliográficos
Autores principales: Provost, Véronique, Langlois, Anick, Chouinard, François, Rola-Pleszczynski, Marek, Chakir, Jamila, Flamand, Nicolas, Laviolette, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432028/
https://www.ncbi.nlm.nih.gov/pubmed/22952702
http://dx.doi.org/10.1371/journal.pone.0043544