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Leukotriene D(4) and Interleukin-13 Cooperate to Increase the Release of Eotaxin-3 by Airway Epithelial Cells
INTRODUCTION: Airway epithelial cells play a central role in the physiopathology of asthma. They release eotaxins when treated with T(H)2 cytokines such as interleukin (IL)-4 or IL-13, and these chemokines attract eosinophils and potentiate the biosynthesis of cysteinyl leukotrienes (cysLTs), which...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432028/ https://www.ncbi.nlm.nih.gov/pubmed/22952702 http://dx.doi.org/10.1371/journal.pone.0043544 |