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Generation of a Novel MMTV-tTA Transgenic Mouse Strain for the Targeted Expression of Genes in the Embryonic and Postnatal Mammary Gland

We have generated a new and improved transgenic mouse strain that permits a temporally controlled expression of transgenes throughout mammary gland development. High expression of the tetracycline-regulatible transactivator (tTA) under control of the mouse mammary tumor virus long terminal repeat (M...

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Detalles Bibliográficos
Autores principales: Sakamoto, Kazuhito, Schmidt, Jeffrey W., Wagner, Kay-Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432039/
https://www.ncbi.nlm.nih.gov/pubmed/22952764
http://dx.doi.org/10.1371/journal.pone.0043778