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SHP-1 Phosphatase Is a Critical Regulator in Preventing Natural Killer Cell Self-Killing
Balance of signals generated from the engaged activating and inhibitory surface receptors regulates mature NK cell activities. The inhibitory receptors signal through immunoreceptor tyrosine based inhibitory motifs (ITIM), and recruit phosphatases such as SHP-1 to inhibit NK cell activation. To dire...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432062/ https://www.ncbi.nlm.nih.gov/pubmed/22952938 http://dx.doi.org/10.1371/journal.pone.0044244 |