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Advantages and Limitations of Different p62-Based Assays for Estimating Autophagic Activity in Drosophila

Levels of the selective autophagy substrate p62 have been established in recent years as a specific readout for basal autophagic activity. Here we compared different experimental approaches for using this assay in Drosophila larvae. Similar to the more commonly used western blots, quantifying p62 do...

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Detalles Bibliográficos
Autores principales: Pircs, Karolina, Nagy, Peter, Varga, Agnes, Venkei, Zsolt, Erdi, Balazs, Hegedus, Krisztina, Juhasz, Gabor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432079/
https://www.ncbi.nlm.nih.gov/pubmed/22952930
http://dx.doi.org/10.1371/journal.pone.0044214