Environmental Enrichment Alters Nicotine-Mediated Locomotor Sensitization and Phosphorylation of DARPP-32 and CREB in Rat Prefrontal Cortex

Exposure within an environmental enrichment paradigm results in neurobiological adaptations and decreases the baseline of locomotor activity. The current study determined activation of DARPP-32 (dopamine- and cAMP-regulated phosphoprotein-32) and CREB (cAMP response element binding protein), and loc...

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Detalles Bibliográficos
Autores principales: Gomez, Adrian M., Midde, Narasimha M., Mactutus, Charles F., Booze, Rosemarie M., Zhu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432100/
https://www.ncbi.nlm.nih.gov/pubmed/22952905
http://dx.doi.org/10.1371/journal.pone.0044149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432100/
https://www.ncbi.nlm.nih.gov/pubmed/22952905
http://dx.doi.org/10.1371/journal.pone.0044149

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