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Environmental Enrichment Alters Nicotine-Mediated Locomotor Sensitization and Phosphorylation of DARPP-32 and CREB in Rat Prefrontal Cortex

Exposure within an environmental enrichment paradigm results in neurobiological adaptations and decreases the baseline of locomotor activity. The current study determined activation of DARPP-32 (dopamine- and cAMP-regulated phosphoprotein-32) and CREB (cAMP response element binding protein), and loc...

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Detalles Bibliográficos
Autores principales:	Gomez, Adrian M., Midde, Narasimha M., Mactutus, Charles F., Booze, Rosemarie M., Zhu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432100/ https://www.ncbi.nlm.nih.gov/pubmed/22952905 http://dx.doi.org/10.1371/journal.pone.0044149

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