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Activity of Trifluoperazine against Replicating, Non-Replicating and Drug Resistant M. tuberculosis

Trifluoperazine, a knowm calmodulin antagonist, belongs to a class of phenothiazine compounds that have multiple sites of action in mycobacteria including lipid synthesis, DNA processes, protein synthesis and respiration. The objective of this study is to evaluate the potential of TFP to be used as...

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Detalles Bibliográficos
Autores principales: Advani, Meeta J., Siddiqui, Imran, Sharma, Pawan, Reddy, Hemalatha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432105/
https://www.ncbi.nlm.nih.gov/pubmed/22952939
http://dx.doi.org/10.1371/journal.pone.0044245