Cargando…

Activity of Trifluoperazine against Replicating, Non-Replicating and Drug Resistant M. tuberculosis

Trifluoperazine, a knowm calmodulin antagonist, belongs to a class of phenothiazine compounds that have multiple sites of action in mycobacteria including lipid synthesis, DNA processes, protein synthesis and respiration. The objective of this study is to evaluate the potential of TFP to be used as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Advani, Meeta J., Siddiqui, Imran, Sharma, Pawan, Reddy, Hemalatha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432105/ https://www.ncbi.nlm.nih.gov/pubmed/22952939 http://dx.doi.org/10.1371/journal.pone.0044245

Ejemplares similares

Calmodulin-like protein from M. tuberculosis H37Rv is required during infection
por: Advani, Meeta J., et al.
Publicado: (2014)

Capreomycin is active against non-replicating M. tuberculosis
por: Heifets, Leonid, et al.
Publicado: (2005)

Trifluoperazine-Induced Angioedema
por: Osman, Mugtaba, et al.
Publicado: (2014)

The Food and Drug Administration-approved antipsychotic drug trifluoperazine, a calmodulin antagonist, inhibits viral replication through PERK-eIF2α axis
por: Mao, Yizhi, et al.
Publicado: (2022)

Pseudo-tetanus following trifluoperazine.
por: Shorten, G. D., et al.
Publicado: (1990)

Trifluoperazine-Induced Cholestatic Jaundice
por: Sharifi, Vandad, et al.
Publicado: (2010)

Hypokalemia with Trifluoperazine at Therapeutic Dose
por: Rehman, Sajjadur, et al.
Publicado: (2017)

Inhibition of dengue virus infection by trifluoperazine
por: Piccini, Luana E., et al.
Publicado: (2022)

A class of hydrazones are active against non-replicating Mycobacterium tuberculosis
por: Bonnett, Shilah A., et al.
Publicado: (2018)

Dissecting the Anticancer Mechanism of Trifluoperazine on Pancreatic Ductal Adenocarcinoma
por: Huang, Can, et al.
Publicado: (2019)

InhA inhibitors have activity against non-replicating Mycobacterium tuberculosis
por: Flint, Lindsay, et al.
Publicado: (2020)

Trifluoperazine, a calmodulin antagonist, inhibits muscle cell fusion
Publicado: (1983)

Trifluoperazine inhibits phagocytosis in a macrophagelike cultured cell line
Publicado: (1981)

Trifluoperazine prevents FOXO1 nuclear excretion and reverses doxorubicin-resistance in the SHG44/DOX drug-resistant glioma cell line
por: Chen, Xiaozhong, et al.
Publicado: (2018)

Benzene Amide Ether Scaffold is Active against Non-replicating and Intracellular Mycobacterium tuberculosis
por: Ahmed, Sara, et al.
Publicado: (2023)

Calmodulin inhibitor trifluoperazine in combination with doxorubicin induces the selection of tumour cells with the multidrug resistant phenotype.
por: Kamath, N., et al.
Publicado: (1993)

Effect of trifluoperazine on Tc-99m sestamibi uptake in patients with advanced nonsmall cell lung cancer
por: Abdülrezzak, Ümmühan, et al.
Publicado: (2016)

Trifluoperazine, an Antipsychotic Drug, Effectively Reduces Drug Resistance in Cisplatin-Resistant Urothelial Carcinoma Cells via Suppressing Bcl-xL: An In Vitro and In Vivo Study
por: Kuo, Kuan-Lin, et al.
Publicado: (2019)

Antipsychotic Drug Trifluoperazine Suppresses Colorectal Cancer by Inducing G0/G1 Arrest and Apoptosis
por: Xia, Yong, et al.
Publicado: (2019)

Modulation in vitro and in vivo of cytotoxicity but not cellular levels of doxorubicin by the calmodulin inhibitor trifluoperazine is dependent on the level of resistance.
por: Ganapathi, R., et al.
Publicado: (1988)

Trifluoperazine and Its Analog Suppressed the Tumorigenicity of Non-Small Cell Lung Cancer Cell; Applicability of Antipsychotic Drugs to Lung Cancer Treatment
por: Jeong, Joo Yeon, et al.
Publicado: (2022)

Targeting DNA Replication and Repair for the Development of Novel Therapeutics against Tuberculosis
por: Reiche, Michael A., et al.
Publicado: (2017)

Simultaneous RP-HPLC Estimation of Trifluoperazine Hydrochloride and Chlordiazepoxide in Tablet Dosage Forms
por: Patel, Sejal K., et al.
Publicado: (2009)

Trifluoperazine Inhibits Mesangial Cell Proliferation by Arresting Cell Cycle-Dependent Mechanisms
por: Wang, Baodong, et al.
Publicado: (2017)

Replicating and non-replicating viral vectors for vaccine development
por: Robert-Guroff, Marjorie
Publicado: (2007)

Implicit Theory of Mind – An overview of current replications and non-replications
por: Kulke, Louisa, et al.
Publicado: (2017)

Trifluoperazine, a novel autophagy inhibitor, increases radiosensitivity in glioblastoma by impairing homologous recombination
por: Zhang, Xin, et al.
Publicado: (2017)

Low concentration trifluoperazine promotes proliferation and reduces calcium-dependent apoptosis in glioma cells
por: Wen, Yulin, et al.
Publicado: (2018)

Trifluoperazine induces cellular apoptosis by inhibiting autophagy and targeting NUPR1 in multiple myeloma
por: Li, Anmao, et al.
Publicado: (2020)

An Unusual Occurrence of Trifluoperazine-Induced Nystagmus in Persistent Hallucinatory Disorder—A Case Report
por: Muthuramalingam, Avin, et al.
Publicado: (2020)

Transcriptome signature analysis repurposes trifluoperazine for the treatment of fragile X syndrome in mouse model
por: Ding, Qi, et al.
Publicado: (2020)

Preclinical Investigation of Trifluoperazine as a Novel Therapeutic Agent for the Treatment of Pulmonary Arterial Hypertension
por: Grobs, Yann, et al.
Publicado: (2021)

Modulation of POPDC1 Expression by Phenothiazine and Trifluoperazine Suppress Colon Cancer Growth and Migration
por: Thomas, Fiona Macniesia, et al.
Publicado: (2022)

A non-transcriptional function of Yap regulates the DNA replication program in Xenopus laevis
por: Meléndez García, Rodrigo, et al.
Publicado: (2022)

Replicability and replication in the humanities
por: Peels, Rik
Publicado: (2019)

M. tuberculosis enhances its virulence during replication in blood from HIV patients
por: Ryndak, Michelle B, et al.
Publicado: (2014)

Bis-biguanide dihydrochloride inhibits intracellular replication of M. tuberculosis and controls infection in mice
por: Shen, Hongbo, et al.
Publicado: (2016)

Editorial: New Approaches Against Drug-Resistant M. tuberculosis
por: Av-Gay, Yossef, et al.
Publicado: (2021)

Replication of Staphylococcal Resistance Plasmids
por: Kwong, Stephen M., et al.
Publicado: (2017)

Hey, I'm still replicating!
por: Williams, Ruth
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_3mc83l44p4id6iprl76n17pjgg