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miR-421 and miR-30c Inhibit SERPINE 1 Gene Expression in Human Endothelial Cells

In this work, we assessed whether SERPINE1 expression could be under the influence of microRNAs (miRNAs) predicted to bind the SERPINE1 3′UTR region. We specifically focused on the 3′UTR region harboring a common polymorphism, rs1050955, that have been found associated to SERPINE1 monocyte expressio...

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Detalles Bibliográficos
Autores principales: Marchand, Alexandre, Proust, Carole, Morange, Pierre-Emmanuel, Lompré, Anne-Marie, Trégouët, David-Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432110/
https://www.ncbi.nlm.nih.gov/pubmed/22952991
http://dx.doi.org/10.1371/journal.pone.0044532