Impaired Virus Clearance, Compromised Immune Response and Increased Mortality in Type 2 Diabetic Mice Infected with West Nile Virus

Clinicoepidemiological data suggest that type 2 diabetes is associated with increased risk of West Nile virus encephalitis (WNVE). However, no experimental studies have elucidated the role of diabetes in WNV neuropathogenesis. Herein, we employed the db/db mouse model to understand WNV immunopathoge...

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Detalles Bibliográficos
Autores principales: Kumar, Mukesh, Roe, Kelsey, Nerurkar, Pratibha V., Namekar, Madhuri, Orillo, Beverly, Verma, Saguna, Nerurkar, Vivek R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432127/
https://www.ncbi.nlm.nih.gov/pubmed/22953001
http://dx.doi.org/10.1371/journal.pone.0044682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432127/
https://www.ncbi.nlm.nih.gov/pubmed/22953001
http://dx.doi.org/10.1371/journal.pone.0044682

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