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Impaired Virus Clearance, Compromised Immune Response and Increased Mortality in Type 2 Diabetic Mice Infected with West Nile Virus
Clinicoepidemiological data suggest that type 2 diabetes is associated with increased risk of West Nile virus encephalitis (WNVE). However, no experimental studies have elucidated the role of diabetes in WNV neuropathogenesis. Herein, we employed the db/db mouse model to understand WNV immunopathoge...
Autores principales: | Kumar, Mukesh, Roe, Kelsey, Nerurkar, Pratibha V., Namekar, Madhuri, Orillo, Beverly, Verma, Saguna, Nerurkar, Vivek R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432127/ https://www.ncbi.nlm.nih.gov/pubmed/22953001 http://dx.doi.org/10.1371/journal.pone.0044682 |
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