Cargando…

EML4-ALK testing in non-small cell carcinomas of the lung: a review with recommendations

In non-small cell lung cancer, epidermal growth factor receptor gene mutations and anaplastic lymphoma kinase (ALK) gene rearrangements have a major impact upon the level of response to treatment with specific tyrosine kinase inhibitors. This review describes the molecular basis of ALK inhibition, s...

Descripción completa

Detalles Bibliográficos
Autores principales: Thunnissen, Erik, Bubendorf, Lukas, Dietel, Manfred, Elmberger, Göran, Kerr, Keith, Lopez-Rios, Fernando, Moch, Holger, Olszewski, Wlodzimierz, Pauwels, Patrick, Penault-Llorca, Frédérique, Rossi, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432214/
https://www.ncbi.nlm.nih.gov/pubmed/22825000
http://dx.doi.org/10.1007/s00428-012-1281-4