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Sp1 expression regulates lung tumor progression

The role of specificity protein 1 (Sp1) in controlling gene expression in lung tumor development and metastasis is not well understood. In this study, we showed that the Sp1 level was highly increased and required for lung tumor growth in transgenic mice bearing Kras-induced lung tumors under the co...

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Detalles Bibliográficos
Autores principales: Hsu, T-I, Wang, M-C, Chen, S-Y, Yeh, Y-M, Su, W-C, Chang, W-C, Hung, J-J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432230/
https://www.ncbi.nlm.nih.gov/pubmed/22158040
http://dx.doi.org/10.1038/onc.2011.568