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Non-transgenic genome modifications in a hemimetabolous insect using zinc-finger and TAL effector nucleases

Hemimetabolous, or incompletely metamorphosing, insects are phylogenetically relatively basal and comprise many pests. However, the absence of a sophisticated genetic model system, or targeted gene-manipulation system, has limited research on hemimetabolous species. Here we use zinc-finger nuclease...

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Detalles Bibliográficos
Autores principales: Watanabe, Takahito, Ochiai, Hiroshi, Sakuma, Tetsushi, Horch, Hadley W., Hamaguchi, Naoya, Nakamura, Taro, Bando, Tetsuya, Ohuchi, Hideyo, Yamamoto, Takashi, Noji, Sumihare, Mito, Taro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432469/
https://www.ncbi.nlm.nih.gov/pubmed/22910363
http://dx.doi.org/10.1038/ncomms2020