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Non-transgenic genome modifications in a hemimetabolous insect using zinc-finger and TAL effector nucleases
Hemimetabolous, or incompletely metamorphosing, insects are phylogenetically relatively basal and comprise many pests. However, the absence of a sophisticated genetic model system, or targeted gene-manipulation system, has limited research on hemimetabolous species. Here we use zinc-finger nuclease...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432469/ https://www.ncbi.nlm.nih.gov/pubmed/22910363 http://dx.doi.org/10.1038/ncomms2020 |