Cargando…

FoxP3(+) regulatory CD4 T cells control the generation of functional CD8 memory

During the primary immune response, CD8 memory emerges from an environment of strong immune activation. The FoxP3(+) regulatory CD4 T-cell subset (Treg) is known as a key suppressive component of the immune system. Here we report that Tregs are required for the generation of functional CD8 memory. I...

Descripción completa

Detalles Bibliográficos
Autores principales: de Goër de Herve, M.G., Jaafoura, S., Vallée, M., Taoufik, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432473/
https://www.ncbi.nlm.nih.gov/pubmed/22871805
http://dx.doi.org/10.1038/ncomms1992