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FoxP3(+) regulatory CD4 T cells control the generation of functional CD8 memory
During the primary immune response, CD8 memory emerges from an environment of strong immune activation. The FoxP3(+) regulatory CD4 T-cell subset (Treg) is known as a key suppressive component of the immune system. Here we report that Tregs are required for the generation of functional CD8 memory. I...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432473/ https://www.ncbi.nlm.nih.gov/pubmed/22871805 http://dx.doi.org/10.1038/ncomms1992 |