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A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells

Non-alcoholic fatty liver disease comprises a broad spectrum of disease states ranging from simple steatosis to non-alcoholic steatohepatitis. As a result of increases in the prevalences of obesity, insulin resistance, and hyperlipidemia, the number of people with hepatic steatosis continues to incr...

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Detalles Bibliográficos
Autores principales: Jozefczuk, Justyna, Kashofer, Karl, Ummanni, Ramesh, Henjes, Frauke, Rehman, Samrina, Geenen, Suzanne, Wruck, Wasco, Regenbrecht, Christian, Daskalaki, Andriani, Wierling, Christoph, Turano, Paola, Bertini, Ivano, Korf, Ulrike, Zatloukal, Kurt, Westerhoff, Hans V., Lehrach, Hans, Adjaye, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432516/
https://www.ncbi.nlm.nih.gov/pubmed/22969728
http://dx.doi.org/10.3389/fphys.2012.00339