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De Novo Donor-Specific HLA Antibody Development and Peripheral CD4(+)CD25(high) Cells in Kidney Transplant Recipients: A Place for Interaction?

The aim of this study was to determine whether the abundance of regulatory T cells (Tregs) (CD4(+)CD25(high)) affects the de novo development of anti-HLA donor-specific antibodies (DSAs) in kidney transplant recipients (KTRs). Methods. Unsensitized (PRA ≤ 10%, no DSA) adult primary KTRs who received...

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Detalles Bibliográficos
Autores principales: Alberu, Josefina, Vargas-Rojas, Maria Inés, Morales-Buenrostro, Luis E., Crispin, Jose C., Rodríguez-Romo, Roxana, Uribe-Uribe, Norma O., Carrasco, Gabriel, Gómez-Martín, Diana, Alcocer-Varela, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432543/
https://www.ncbi.nlm.nih.gov/pubmed/22970343
http://dx.doi.org/10.1155/2012/302539