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Selective Deletion of the Leptin Receptor in Dopamine Neurons Produces Anxiogenic-like Behavior and Increases Dopaminergic Activity in Amygdala

Leptin receptors (Lepr) are expressed on midbrain dopamine neurons. However, the specific role of Lepr signaling in dopamine neurons remains to be clarified. In the present study, we generated a line of conditional knockout mice lacking functional leptin receptors selectively on dopamine neurons (Le...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Perez, Stephanie M., Zhang, Wei, Lodge, Daniel J., Lu, Xin-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432580/
https://www.ncbi.nlm.nih.gov/pubmed/21483433
http://dx.doi.org/10.1038/mp.2011.36