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Protein kinase C-delta regulates HIV-1 replication at an early post-entry step in macrophages

BACKGROUND: Macrophages, which are CD4 and CCR5 positive, can sustain HIV-1 replication for long periods of time. Thus, these cells play critical roles in the transmission, dissemination and persistence of viral infection. Of note, current antiviral therapies do not target macrophages efficiently. P...

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Detalles Bibliográficos
Autores principales: Contreras, Xavier, Mzoughi, Olfa, Gaston, Fabrice, Peterlin, Matija B, Bahraoui, Elmostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432598/
https://www.ncbi.nlm.nih.gov/pubmed/22554282
http://dx.doi.org/10.1186/1742-4690-9-37