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Updates on HIPK2: a resourceful oncosuppressor for clearing cancer

Homeodomain-interacting protein kinase 2 (HIPK2) is a multitalented protein that exploits its kinase activity to modulate key molecular pathways in cancer to restrain tumor growth and induce response to therapies. HIPK2 phosphorylates oncosuppressor p53 for apoptotic activation. In addition, also p5...

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Detalles Bibliográficos
Autores principales: D’Orazi, Gabriella, Rinaldo, Cinzia, Soddu, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432601/
https://www.ncbi.nlm.nih.gov/pubmed/22889244
http://dx.doi.org/10.1186/1756-9966-31-63