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A mixed-model approach for genome-wide association studies of correlated traits in structured populations

Genome-wide association studies (GWAS) are a standard approach for studying the genetics of natural variation. A major concern in GWAS is the need to account for the complicated dependence-structure of the data both between loci as well as between individuals. Mixed models have emerged as a general...

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Detalles Bibliográficos
Autores principales: Korte, Arthur, Vilhjálmsson, Bjarni J., Segura, Vincent, Platt, Alexander, Long, Quan, Nordborg, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432668/
https://www.ncbi.nlm.nih.gov/pubmed/22902788
http://dx.doi.org/10.1038/ng.2376